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Cosmetic Ingredients

Bio-Ferment Advanced Skin Recovery Actives

Bio-Ferment Advanced Skin Recovery Actives

NFC’s Bio-Ferment Advanced Skin Recovery Actives portfolio is a high-performance bioactive line that precisely activates skin recovery mechanisms based on probiotic fermentation technology. Through fermented PDRN, plant-fermented extracts, and biopolysaccharides, it delivers multi-dimensional benefits including anti-inflammatory, antioxidant, regenerative, and barrier-strengthening effects. Scientifically supported data, including in vivo validation, substantiate its efficacy in damaged skin recovery and anti-aging performance. Designed with low-irritation and high-stability systems, it is applicable to a wide range of formulations, offering next-generation derma and premium skincare solutions.

Product List

Product Name
Ingredients
Characteristic/Benefit
Turmericgel
Ingredients : Lactobacillus Ferment,
1,2-Hexanediol, Etc
  • • Enhanced lactic acid fermentation; anti-inflammatory + moisturizing + soothing + barrier-strengthening 4-in-1
  • • Fully vegan-certified
  • • Strengthened Lactobacillus fermentation extract, co-developed by NFC & Il-Dong Pharmaceutical
  • • Excellent formulation stability
  • • Suitable for all formulation types (0.5–10%)
  • • Premium fermented ingredient adopted by leading K-Beauty flagship brands
TECAsome 4.0
Ingredients : Asiaticoside, Madecassic Acid, Glycerin, Water, Etc
  • • TECA 4% nano-liposomal stabilization: Enables stable incorporation even in aqueous formulations. Resolves TECA formulation stability issues, enhances stability and skin absorption, thereby maximizing efficacy
  • • Powerful antioxidant & anti-aging care
  • • Skin damage recovery, soothing effects & promotion of skin regeneration
  • • Excellent formulation compatibility: Dispersible in both oil and water phases; easily applicable to high-viscosity emulsions, essences, serums, and various other formulation types
  • • Proven ingredient adopted by leading K-Beauty brands: Widely applied across multiple brand products
Lacto-PDRN500 / Lacto-PDRN5000 / Lacto-PDRN100K
Ingredients : Sodium DNA, Etc
  • • Multi-performance DNA active derived from Lactic acid Bacterial fermentation
  • • Enhances cell activation, immune modulation, antioxidant activity, and regeneration
  • • In-vivo (clinically validated) multi anti-aging effects: brightening, elasticity, wrinkle improvement, and skin tone enhancement
  • • First-ever PDRN obtained via Lactobacillus rhamnosus fermentation and extraction
  • • Low-molecular DNA structure (Avg. 32,500–65,000 Da) for enhanced skin absorption and cellular activity
  • • Strong anti-inflammatory, immunomodulatory, and antioxidant effects; promotes cell regeneration and tissue repair
  • • Stimulates EGF, FGF, and IGF, contributing to skin regeneration and barrier recovery
  • • High stability and sustainable sourcing, ensuring long-term formulation reliability
NF-FucoN1000
Ingredients : Biosaccharide Gum-1, Water, Etc
  • • Fermentation-derived polysaccharide: Biosaccharide Gum-1 obtained through microbial fermentation, delivering moisturization, anti-inflammatory, and regenerative benefits simultaneously as a multi-performance bioactive
  • • Outstanding long-lasting hydration efficacy
  • • Anti-inflammatory, soothing & immunomodulatory functions
  • • Promotes skin regeneration & wound recovery
  • • Distinctive fermented sensory profile: Provides the smooth and silky texture characteristic of fermented ingredients
  • • Excellent formulation stability & versatility: Applicable across all formulation types at 0.5–10% usage levels; demonstrates strong salt and temperature stability (note: viscosity may decrease under low pH conditions)
NF Pro-X
Ingredients : Hydroxypropyl -
Tetrahydropyrantriol,
Water, Etc
  • • Hydroxypropyl Tetrahydropyrantriol-based anti-aging active: A multi-anti-aging solution that simultaneously delivers firmness, wrinkle improvement, and skin regeneration • Improves dermal skin structure
  • • Promotes collagen synthesis & supports skin regeneration
  • • Strengthens the DEJ (dermal–epidermal junction): Provides anti-aging and wrinkle-reducing benefits (Liquid type)
  • • Proven safety profile: Demonstrated over 90% cell viability at 300–3,000 ppm with no observed cytotoxicity
  • • Broad formulation compatibility: Water-soluble ingredient, easily applicable at 0.5–5% in various skincare formulations**
Preserveil
Ingredients : Lactobacillus Ferment
  • • Fermentation-derived Reuterin-based natural preservative: A fermentation-based alternative to chemically synthesized preservatives, offering non-toxicity, broad-spectrum antimicrobial activity, and sustainability
  • • Key active ingredient – Reuterin: A natural antimicrobial compound produced through fermentation by Lactobacillus reuteri, containing a high concentration of Reuterin (100 ± 10 mM)
  • • Broad-spectrum antimicrobial efficacy: Demonstrates strong antimicrobial activity against the five USP challenge test strains
  • • Safe, non-toxic, eco-friendly & sustainable
  • • Excellent stability: Maintains stable antimicrobial performance across pH 4.5–8.0 and under high-temperature onditions
Tremella Heteropolysaccharide (WSK)
Ingredients : Tremella Fuciformis
Polysaccharide
  • • 100% natural high-molecular-weight polysaccharide bioactive: Extracted from Tremella fuciformis (white jelly mushroom), composed entirely of natural origin ingredients
  • • Exceptional moisturization performance: Superior water retention and skin hydration capacity compared to sodium hyaluronate
  • • Enhances skin barrier & protective film formation: Provides antioxidant and anti-aging benefits
  • • Broad formulation applicability
  • • Excellent stability: Maintains viscosity stability across pH 3–11, as well as under high-temperature and salt conditions
  • • Premium sensory profile: Soft and smooth texture with low tackiness and high skin compatibility**
DNA-NA(L)S
Ingredients : Tremella
Heteropolysaccharide, Etc
  • • Low-molecular-weight, water-soluble salmon PDRN: Extracted from salmon milt (white salmon testes), delivering skin regeneration and anti-aging benefits
  • • 100% water-soluble ingredient: Rapidly dissolves in water at room temperature, maintaining clarity without precipitation or floating particles. Suitable for films, melting formulations, and liquid systems
  • • Colorless, odorless & non-irritating: Minimizes fishy odor and off-notes, ensuring high formulation acceptability
  • • Anti-aging & regenerative efficacy: As a cellular component, contributes to the maintenance and expression of genetic information, helping compensate for age-related decline in nucleic acid synthesis**
Lacto-HYAL
Ingredients : Lactobacillus Ferment Lysate, Hydrolyzed sodium Hyalurona te, 1,2-Hexanediol
  • • Next-generation bio hyaluronic acid complex based on lactic acid fermentation
  • • Provides synergistic moisturizing effects through ultra-low, low, and high molecular weight HA
  • • Optimized moisture delivery across skin layers with a structure specialized for deep hydration
  • • Moisture-retaining system that forms a thin, uniform film on the skin (reduced need for preservatives such as Phenoxyethanol)
  • • Multi-function HA complex delivering elasticity improvement, soothing effects, and long-lasting hydration simultaneously
  • • Can be applied to various formulations such as serums, lotions, and masks, with excellent formulation stability
  • • All-in-one solution for moisturizing, elasticity, and barrier care
Smilax™
Ingredients : Lactobacillus/Smilax China Leaf Ferment Filtrate
  • • Anti-pollution bioactive based on fermented galactomyces × probiotic technology
  • • Provides protection against external environmental stress such as fine dust and UV exposure
  • • Clinically validated improvements in skin brightness and tone
  • • Antioxidant activity enhancement and oxidative stress reduction confirmed (in vitro)
  • • Human application tests verified improvements in skin brightness, hydration, and overall skin condition
  • • Reduction of skin redness (erythema) confirmed after 4 weeks of use
  • • Low irritation / non-irritating, suitable for sensitive skin
  • • Applicable to various formulations such as masks, serums, and creams, enabling anti-pollution functional skincare design: Premium bioactive blend with skin barrier strengthening benefits